Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1990-12-19
|
| pubmed:abstractText |
This paper describes the quantitative structure-stability relationship of TcvON2S2 compounds using a stability indicator based on the solid angle factor sum (SAS) for predicting the in vitro stability. The SAS values of six TcvON2S2 and one TcvON4 (D,L-HMPAO) complexes were calculated from their x-ray crystallography data. The rank order of in vitro stability of these compounds, as measured by ligand exchange reaction, is directly related to that of the SAS values. The SAS values are potentially useful for predicting stability and designing new 99mTc radiopharmaceuticals.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0883-2889
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
41
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
773-81
|
| pubmed:dateRevised |
2009-6-4
|
| pubmed:meshHeading | |
| pubmed:year |
1990
|
| pubmed:articleTitle |
Quantitative study of the structure-stability relationship of TcvO(III) complexes.
|
| pubmed:affiliation |
Department of Radiology, University of Pennsylvania, Philadelphia 19104.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|