Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-12-20
pubmed:abstractText
Lactotropic adenohypophyseal function and lactation intensity were studied under simultaneous blockade of dopamine receptors and stimulation of serotonin metabolism in the rat hypothalamus. Blockade of hypothalamic dopamine receptors by tricedil decreased the dopamine level, increased the serotonin content and intensified its metabolism thus increasing the prolactin secretion. Under these conditions, tryptophan application potentiated the above changes in hypothalamic catecholamine and indolamine metabolism, increased the prolactin secretion. The latter is associated with the brain serotoninergic system reactivity to suckling impulses: an important factor in the lactation reflex. Tryptophan maintains a high level of hypothalamic serotonin metabolism, maintaining an increase in the prolactin secretion level and secretory activity of the mammary glands.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0015-329X
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
795-801
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[The stimulation of prolactin secretion by the simultaneous inhibition of the dopaminergic and activation of the serotoninergic systems in the hypothalamus].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract