Linked Life Data

2171980

Source:http://linkedlifedata.com/resource/pubmed/id/2171980

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-12-6
pubmed:abstractText
The capacity of dibutyryladenosine-3':5'-cyclic phosphate (dibutyryl cAMP), verapamil and epinephrine to modulate cholesterol (CH) excretion was studied in the stored (4-14C)-CH rat macrophages. The experiments indicated that in the absence of high density lipoproteins (HDL) the addition of dibutyryl cAMP (0.2 mmol), verapamil (0.05 mmol), epinephrine (0.05 mmol) in cultured medium did not influence the excretion of the stored (4-14C)-CH from macrophages during 4, 8 and 18 hours. The addition of the drugs in the presence of HDL resulted in an increase in the excretion of (4-14C)-CH from macrophages during incubation. The data indicate that the drugs which increase the cellular concentration of cAMP can induce the mobilization of CH from macrophages in the presence of acceptors of CH.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-8318
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
44-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[The effect of dibutyryl cAMP, verapamil and adrenaline on cholesterol mobilization from macrophages].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract