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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-7-1
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pubmed:abstractText |
Use of folic acid radioconjugates for folate receptor (FR) targeting is a promising strategy for imaging purposes as well as for potential therapy of cancer and inflammatory diseases due to the frequent FR overexpression found on cancer cells and activated macrophages. Herein, we report on preclinical results using a novel DOTA-Bz-EDA-folate conjugate radiolabeled with [(67)Ga]-gallium.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-(4-isothiocyanatobenzyl)-1,4,7,10-...,
http://linkedlifedata.com/resource/pubmed/chemical/Folic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Folic Acid Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Gallium Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamates,
http://linkedlifedata.com/resource/pubmed/chemical/Guanine,
http://linkedlifedata.com/resource/pubmed/chemical/Heterocyclic Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Isothiocyanates,
http://linkedlifedata.com/resource/pubmed/chemical/Radioactive Tracers,
http://linkedlifedata.com/resource/pubmed/chemical/pemetrexed
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1872-9614
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
715-23
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pubmed:meshHeading |
pubmed-meshheading:21718947-Animals,
pubmed-meshheading:21718947-Biological Transport,
pubmed-meshheading:21718947-Female,
pubmed-meshheading:21718947-Folic Acid,
pubmed-meshheading:21718947-Folic Acid Antagonists,
pubmed-meshheading:21718947-Gallium Radioisotopes,
pubmed-meshheading:21718947-Glutamates,
pubmed-meshheading:21718947-Guanine,
pubmed-meshheading:21718947-Half-Life,
pubmed-meshheading:21718947-Heterocyclic Compounds,
pubmed-meshheading:21718947-Humans,
pubmed-meshheading:21718947-Hydrogen-Ion Concentration,
pubmed-meshheading:21718947-Injections,
pubmed-meshheading:21718947-Isothiocyanates,
pubmed-meshheading:21718947-KB Cells,
pubmed-meshheading:21718947-Kidney,
pubmed-meshheading:21718947-Mice,
pubmed-meshheading:21718947-Radioactive Tracers,
pubmed-meshheading:21718947-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:21718947-Tomography, X-Ray Computed,
pubmed-meshheading:21718947-Urine,
pubmed-meshheading:21718947-Uterine Cervical Neoplasms
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pubmed:year |
2011
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pubmed:articleTitle |
Tumor targeting using 67Ga-DOTA-Bz-folate--investigations of methods to improve the tissue distribution of radiofolates.
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pubmed:affiliation |
Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. cristina.mueller@psi.ch
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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