Linked Life Data

21715631

Source:http://linkedlifedata.com/resource/pubmed/id/21715631

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
26
pubmed:dateCreated
2011-6-30
pubmed:abstractText
Gamma-band (25-90 Hz) peaks in local field potential (LFP) power spectra are present throughout the cerebral cortex and have been related to perception, attention, memory, and disorders (e.g., schizophrenia and autism). It has been theorized that gamma oscillations provide a "clock" for precise temporal encoding and "binding" of signals about stimulus features across brain regions. For gamma to function as a clock, it must be autocoherent: phase and frequency conserved over a period of time. We computed phase and frequency trajectories of gamma-band bursts, using time-frequency analysis of LFPs recorded in macaque primary visual cortex (V1) during visual stimulation. The data were compared with simulations of random networks and clock signals in noise. Gamma-band bursts in LFP data were statistically indistinguishable from those found in filtered broadband noise. Therefore, V1 LFP data did not contain clock-like gamma-band signals. We consider possible functions for stochastic gamma-band activity, such as a synchronizing pulse signal.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1529-2401
pubmed:author
pubmed:issnType
Electronic
pubmed:day
29
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9658-64
pubmed:dateRevised
2011-9-22
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Is gamma-band activity in the local field potential of V1 cortex a "clock" or filtered noise?
pubmed:affiliation
Center for Neural Science and Courant Institute of Mathematical Sciences, New York University, New York 10012, USA. sburns9@jhu.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural