Linked Life Data

21715437

Source:http://linkedlifedata.com/resource/pubmed/id/21715437

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2011-8-8
pubmed:abstractText
Humans respond differently toward exposure against pathogens and some individuals are completely resistant against transmission due to a genetically determined susceptibility. A rising number of such, so-called, host factors have been described during the last years, but their role for diagnostic or therapeutic application is still to be clarified. Here, we describe the biology of the chemokine receptor CCR5 and its polymorphism in the context of host adaptation and immune system function. Furthermore, the first clinical applications exploiting our knowledge of this chemokine receptor as a host factor are described.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1535-3699
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
236
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
938-43
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
The CCR5-delta32 polymorphism as a model to study host adaptation against infectious diseases and to develop new treatment strategies.
pubmed:affiliation
Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, German Red Cross Blood Service Baden-Württemberg-Hessen, Heidelberg University, 68167 Mannheim, Germany. gero.huetter@medma.uni-heidelberg.de
pubmed:publicationType
Journal Article, Review