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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2011-6-28
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pubmed:abstractText |
Primary open angle glaucoma (POAG) is considered to be a leading cause of irreversible blindness worldwide. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) have been extensively studied as POAG risk factors. Recently, several single-nucleotide polymorphisms (SNPs) for MMPs and TIMPs encoding genes have been reported in POAG patients. The aim of this study was to investigate association of the -1607 1G/2G MMP1 and 372 T/C TIMP1 gene polymorphisms with risk of POAG in a Polish population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1643-3750
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
CR417-21
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pubmed:meshHeading |
pubmed-meshheading:21709637-Aged,
pubmed-meshheading:21709637-Aged, 80 and over,
pubmed-meshheading:21709637-DNA Primers,
pubmed-meshheading:21709637-Female,
pubmed-meshheading:21709637-Gene Frequency,
pubmed-meshheading:21709637-Genetic Predisposition to Disease,
pubmed-meshheading:21709637-Genome-Wide Association Study,
pubmed-meshheading:21709637-Glaucoma, Open-Angle,
pubmed-meshheading:21709637-Humans,
pubmed-meshheading:21709637-Male,
pubmed-meshheading:21709637-Matrix Metalloproteinase 1,
pubmed-meshheading:21709637-Middle Aged,
pubmed-meshheading:21709637-Poland,
pubmed-meshheading:21709637-Polymorphism, Single Nucleotide,
pubmed-meshheading:21709637-Tissue Inhibitor of Metalloproteinase-1
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pubmed:year |
2011
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pubmed:articleTitle |
Association of MMP1-1607 1G/2G and TIMP1 372 T/C gene polymorphisms with risk of primary open angle glaucoma in a Polish population.
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pubmed:affiliation |
Department of Clinical Chemistry and Biochemistry, Medical University of Lodz, Lodz, Poland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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