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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1990-11-19
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pubmed:abstractText |
Several aspects of cyclic AMP second messenger signal generation were examined in EBV-transformed cell lines from 12 schizophrenic patients and 12 age- and sex-matched controls. No evidence was obtained suggesting a heritable abnormality in cyclic AMP synthesis in schizophrenia. Basal, forskolin, A1/NaF- and GppNHp-stimulated cyclic AMP synthesis in membranes from transformed cell lines was identical for schizophrenic and control subjects. In addition, no significant differences were observed for basal, forskolin-, isoproterenol- and prostaglandin E1-stimulated cyclic AMP accumulation in intact cell lines derived from ten of the schizophrenic patients compared with cell lines derived from ten of the control subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0022-3956
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
121-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2170638-Adenylate Cyclase,
pubmed-meshheading:2170638-Cell Line, Transformed,
pubmed-meshheading:2170638-Cyclic AMP,
pubmed-meshheading:2170638-Herpesvirus 4, Human,
pubmed-meshheading:2170638-Humans,
pubmed-meshheading:2170638-Risk Factors,
pubmed-meshheading:2170638-Schizophrenia,
pubmed-meshheading:2170638-Schizophrenic Psychology,
pubmed-meshheading:2170638-Second Messenger Systems
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pubmed:year |
1990
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pubmed:articleTitle |
Cyclic AMP second messenger signal generation in EBV-transformed lymphoblastoid cells from schizophrenic patients.
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pubmed:affiliation |
Department of Psychiatric Research, Ezrath Nashim Hospital, Jerusalem, Israel.
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pubmed:publicationType |
Journal Article
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