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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2011-6-23
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pubmed:abstractText |
Mesenchymal stromal cells (MSC) are being investigated as immunomodulatory therapy in the field of transplantation, particularly islet transplantation. While MSC can regenerate across species barriers, the immunoregulatory influence of genetically modified pig MSC (pMSC) on the human and non-human primate T-cell responses has not been studied.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD46,
http://linkedlifedata.com/resource/pubmed/chemical/CD40 Ligand,
http://linkedlifedata.com/resource/pubmed/chemical/CD46 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Galactosyltransferases,
http://linkedlifedata.com/resource/pubmed/chemical/Histocompatibility Antigens Class II,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/N-acetyllactosaminide...,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/swine leukocyte antigen
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pubmed:status |
MEDLINE
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pubmed:issn |
1399-3089
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pubmed:author |
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pubmed:copyrightInfo |
© 2011 John Wiley & Sons A/S.
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pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
183-95
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pubmed:meshHeading |
pubmed-meshheading:21696448-Animals,
pubmed-meshheading:21696448-Animals, Genetically Modified,
pubmed-meshheading:21696448-Antigens, CD46,
pubmed-meshheading:21696448-CD4-Positive T-Lymphocytes,
pubmed-meshheading:21696448-CD40 Ligand,
pubmed-meshheading:21696448-Cell Differentiation,
pubmed-meshheading:21696448-Cells, Cultured,
pubmed-meshheading:21696448-Endothelial Cells,
pubmed-meshheading:21696448-Galactosyltransferases,
pubmed-meshheading:21696448-Histocompatibility Antigens Class II,
pubmed-meshheading:21696448-Humans,
pubmed-meshheading:21696448-Immunoglobulins,
pubmed-meshheading:21696448-Interferon-gamma,
pubmed-meshheading:21696448-Interleukin-2,
pubmed-meshheading:21696448-Mesenchymal Stem Cells,
pubmed-meshheading:21696448-Papio,
pubmed-meshheading:21696448-Stromal Cells,
pubmed-meshheading:21696448-Swine,
pubmed-meshheading:21696448-Tumor Necrosis Factor-alpha
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pubmed:articleTitle |
Genetically-modified pig mesenchymal stromal cells: xenoantigenicity and effect on human T-cell xenoresponses.
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pubmed:affiliation |
Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, 200 Lothrop Street,Pittsburgh, PA 15261, USA. ezzelarabmb@upmc.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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