Linked Life Data

21696377

Source:http://linkedlifedata.com/resource/pubmed/id/21696377

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2011-6-23
pubmed:abstractText
A 10-week-old Thoroughbred filly was referred for anaemia of 4 weeks' duration. Haematology revealed severe anaemia and panleucopenia. Cytological examination of bone marrow smears revealed a myeloid to erythroid ratio <0.02:1 (reference range 0.5-2.4:1.0) and an abundance of erythroid precursor cells. The erythroid cell population included rubriblasts, prorubricytes and rubricytes, with only scant numbers of metarubricytes present. There were numerous mitotic erythroid cells, some of which were atypical and megaloblastic. These cytomorphological changes are consistent with pure acute erythroid leukaemia. No treatment was instituted and the filly died three days after presentation. This case illustrates the need to consider both haematology and bone marrow findings to establish a diagnosis of pure erythroid leukaemia. To our knowledge, there is no documented case of acute myeloproliferative disease in horses involving cells of erythroid lineage, but this condition should be considered a differential diagnosis for horses presenting with anaemia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1751-0813
pubmed:author
pubmed:copyrightInfo
© 2011 The Authors. Australian Veterinary Journal © 2011 Australian Veterinary Association.
pubmed:issnType
Electronic
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-72
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Acute myeloid leukaemia (M6B: pure acute erythroid leukaemia) in a Thoroughbred foal.
pubmed:affiliation
Equine Centre, Veterinary Clinic and Hospital, University of Melbourne, Werribee, Victoria, Australia. gforbes@unimelb.edu.au
pubmed:publicationType
Journal Article, Case Reports