Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1990-10-19
|
| pubmed:abstractText |
To assess the contribution of hepatitis C virus (HCV) in liver disease in Taiwan, antibody to HCV (anti-HCV) was studied by radioimmunoassay in 392 patients with chronic liver disease and in 440 healthy adults and 444 subjects at risk. The anti-HCV prevalence was 0.95% in 420 volunteer blood donors, 90% in 100 hemophiliacs, and 81% in 58 parenteral drug abusers. Anti-HCV was present in 6 (7.7%) of 78 hepatitis B surface antigen (HBsAg)-positive and 28 (65%) of 43 HBsAg-negative patients with chronic hepatitis, 3 (10%) of 31 HBsAg-positive and 13 (43%) of 30 HBsAg-negative cirrhotics, and 7 (17%) of 42 HBsAg-positive and 15 (63%) of 24 HBsAg-negative patients with hepatocellular carcinoma (HCC). An outbreak of non-A, non-B hepatitis revealed 18% of 57 patients to be positive for anti-HCV, and in 29 patients with posttransfusion hepatitis prospectively followed, 7 (24%) developed anti-HCV. Thus, HCV infection appears to play a relatively minor role in HBsAg-positive liver disease in Taiwan but is strongly associated with HBsAg-negative chronic liver disease and HCC. The infection is extremely common in hemophiliacs and parenteral drug abusers.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
162
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
817-22
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2169497-Adult,
pubmed-meshheading:2169497-Aged,
pubmed-meshheading:2169497-Blood Donors,
pubmed-meshheading:2169497-Carcinoma, Hepatocellular,
pubmed-meshheading:2169497-Chronic Disease,
pubmed-meshheading:2169497-Female,
pubmed-meshheading:2169497-Hemophilia A,
pubmed-meshheading:2169497-Hepatitis, Viral, Human,
pubmed-meshheading:2169497-Hepatitis Antibodies,
pubmed-meshheading:2169497-Hepatitis B,
pubmed-meshheading:2169497-Hepatitis B Surface Antigens,
pubmed-meshheading:2169497-Hepatitis C,
pubmed-meshheading:2169497-Hepatitis Viruses,
pubmed-meshheading:2169497-Humans,
pubmed-meshheading:2169497-Liver Diseases,
pubmed-meshheading:2169497-Liver Neoplasms,
pubmed-meshheading:2169497-Male,
pubmed-meshheading:2169497-Middle Aged,
pubmed-meshheading:2169497-Prevalence,
pubmed-meshheading:2169497-Substance Abuse, Intravenous,
pubmed-meshheading:2169497-Taiwan
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Hepatitis C virus infection in an area hyperendemic for hepatitis B and chronic liver disease: the Taiwan experience.
|
| pubmed:affiliation |
Hepatitis Research Center, National Taiwan University Hospital, Republic of China.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|