Linked Life Data

21694931

Source:http://linkedlifedata.com/resource/pubmed/id/21694931

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2011-6-22
pubmed:abstractText
Leukemic infiltration of the kidney is usually silent, and the admission of the patients with renal dysfunction or acute kidney injury is uncommon. We present a 34-year old hemodialysis patient with new onset of uncontrolled hypertension, erythropoietin-resistant anemia, thrombocytopenia, and Bell's palsy. On admission, his blood pressure (BP) was 210/110 mmHg and he had petechiae and purpura at upper and lower extremities. Renal ultrasonography (USG) showed bilaterally enlarged kidneys without hydronephrosis, unlike his previous USG, which determined bilaterally atrophic kidneys. Acute lymphoblastic leukemia, hypertensive crisis due to bilateral leukemic cell infiltration of kidneys, tumor lysis syndrome, and leukemic involvement of the facial nerve were diagnosed. Despite intense antihypertensive management, his BP was not controlled. After prednisolone, daunorubicine, and vincristine therapy, the size of kidneys diminished and his BP dropped under normal range. In conclusion, pathological findings such as uncontrolled hypertension, flank pain, skin rashes, and abnormal blood count should be considered carefully, even in patients with end-stage renal disease receiving renal replacement therapy.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
1178-7058
pubmed:author
pubmed:copyrightInfo
2010 Turkmen et al, publisher and licensee Dove Medical Press Ltd.
pubmed:issnType
Electronic
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-8
pubmed:dateRevised
2011-8-1
pubmed:year
2010
pubmed:articleTitle
Uncontrolled hypertension secondary to leukemic cell infiltration of kidneys in a hemodialysis patient.
pubmed:affiliation
Department of Nephrology, Meram School of Medicine, Selcuk University.
pubmed:publicationType
Journal Article