21693609

Source:http://linkedlifedata.com/resource/pubmed/id/21693609

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0086418, umls-concept:C0175677, umls-concept:C1280500, umls-concept:C2330894
pubmed:issue	9
pubmed:dateCreated	2011-8-10
pubmed:abstractText	Micro(mi)RNAs negatively regulate a wide variety of genes through degradation or posttranslational inhibition of their target genes. The purpose of this study was to investigate the role of miR-23a in modulating RPE cell survival and gene expression in response to oxidative damage.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7703701
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/AIFM1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD95, http://linkedlifedata.com/resource/pubmed/chemical/Apoptosis Inducing Factor, http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3, http://linkedlifedata.com/resource/pubmed/chemical/Cytochromes c, http://linkedlifedata.com/resource/pubmed/chemical/Hydrogen Peroxide, http://linkedlifedata.com/resource/pubmed/chemical/MIRN23 microRNA, human, http://linkedlifedata.com/resource/pubmed/chemical/MicroRNAs, http://linkedlifedata.com/resource/pubmed/chemical/Oxidants, http://linkedlifedata.com/resource/pubmed/chemical/tert-Butylhydroperoxide
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1552-5783
pubmed:author	pubmed-author:CastilloAlexander CAC, pubmed-author:ChenGuanglinG, pubmed-author:KeyesKyle TKT, pubmed-author:LinHaijiangH, pubmed-author:LongBoB, pubmed-author:QianJinqiaoJ, pubmed-author:YeYumeiY
pubmed:issnType	Electronic
pubmed:volume	52
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	6308-14
pubmed:meshHeading	pubmed-meshheading:21693609-Aged, pubmed-meshheading:21693609-Aged, 80 and over, pubmed-meshheading:21693609-Antigens, CD95, pubmed-meshheading:21693609-Apoptosis, pubmed-meshheading:21693609-Apoptosis Inducing Factor, pubmed-meshheading:21693609-Blotting, Northern, pubmed-meshheading:21693609-Blotting, Western, pubmed-meshheading:21693609-Caspase 3, pubmed-meshheading:21693609-Cell Survival, pubmed-meshheading:21693609-Cells, Cultured, pubmed-meshheading:21693609-Cytochromes c, pubmed-meshheading:21693609-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:21693609-Gene Expression Regulation, pubmed-meshheading:21693609-Humans, pubmed-meshheading:21693609-Hydrogen Peroxide, pubmed-meshheading:21693609-Macular Degeneration, pubmed-meshheading:21693609-MicroRNAs, pubmed-meshheading:21693609-Middle Aged, pubmed-meshheading:21693609-Mitochondria, pubmed-meshheading:21693609-Oxidants, pubmed-meshheading:21693609-Oxidative Stress, pubmed-meshheading:21693609-Retinal Pigment Epithelium, pubmed-meshheading:21693609-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:21693609-Tissue Donors, pubmed-meshheading:21693609-Transfection, pubmed-meshheading:21693609-tert-Butylhydroperoxide
pubmed:year	2011
pubmed:articleTitle	Effect of miR-23 on oxidant-induced injury in human retinal pigment epithelial cells.
pubmed:affiliation	Departments of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, Texas 77555, USA.
pubmed:publicationType	Journal Article