|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2011-7-12
|
|
pubmed:abstractText |
In this study, we evaluated (a) the contribution of SLCO1B3 and UGT1A polymorphisms to the pharmacokinetics of telmisartan in two forms, a microdose (MD) and a therapeutic dose (TD); (b) linkage disequilibrium (LD) between UGT1A1 and UGT1A3; and (c) linearity in the pharmacokinetics of telmisartan between the two forms.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1744-6880
|
|
pubmed:author |
pubmed-author:ChiyodaTakeshiT,
pubmed-author:HirotaTekeshiT,
pubmed-author:IeiriIchiroI,
pubmed-author:IrieShinS,
pubmed-author:KimuraMiyukiM,
pubmed-author:MaedaKazuyaK,
pubmed-author:NishimuraChisaC,
pubmed-author:NoguchiTakanoriT,
pubmed-author:SasakiTomohiroT,
pubmed-author:ShimizuHitoshiH,
pubmed-author:SugiyamaYuichiY,
pubmed-author:YoshidaKenjiK
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
21
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
495-505
|
|
pubmed:meshHeading |
pubmed-meshheading:21691256-Adult,
pubmed-meshheading:21691256-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:21691256-Benzimidazoles,
pubmed-meshheading:21691256-Benzoates,
pubmed-meshheading:21691256-Dose-Response Relationship, Drug,
pubmed-meshheading:21691256-Gene Frequency,
pubmed-meshheading:21691256-Genotype,
pubmed-meshheading:21691256-Glucuronosyltransferase,
pubmed-meshheading:21691256-Haplotypes,
pubmed-meshheading:21691256-Humans,
pubmed-meshheading:21691256-Linkage Disequilibrium,
pubmed-meshheading:21691256-Male,
pubmed-meshheading:21691256-Organic Anion Transporters, Sodium-Independent,
pubmed-meshheading:21691256-Pharmacogenetics,
pubmed-meshheading:21691256-Polymorphism, Single Nucleotide
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Pharmacokinetic and pharmacogenomic profiles of telmisartan after the oral microdose and therapeutic dose.
|
|
pubmed:affiliation |
Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
