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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2011-6-20
pubmed:abstractText
Skin infection associated with methicillin-resistant Staphylococcus aureus (MRSA)-ST398 was detected in a pig-farmer, and MRSA-ST398 isolates were also detected in nasal samples of the patient and of 11/12 pigs on his farm. Twelve MRSA isolates were obtained from skin lesions (n = 6) and nasal samples (n = 6) of the patient in two sampling moments and 11 MRSA isolates from nasal samples of pigs. They were typed as t011-SCCmecIVa-agrI and t108-SCCmecV-agrI (patient and pigs) and t588-SCCmecV-agrI (patient). The following resistance genes were detected (number isolates): tet(K) (1), tet(L) (23), tet(M) (13), erm(A) (13), erm(C) (13), msr(A) (11), lnu(A) (21), aph(2'')-acc(6') (3), ant(4') (13), aph(3') (12), dfrS1 (15) and dfrK (22). Seventeen human and animal MRSA-ST398 isolates showed indistinguishable PFGE patterns (A1-spa-t011 or B2-spa-t108) and similar phenotypic-genotypic characteristics, including the presence of the lnu(A) gene, associated with lincomycin resistance. Potential pig-to-human transference of ST398 is suggested in this study. The first detection of the lnu(A) gene in MRSA-ST398 is reported.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1469-0691
pubmed:author
pubmed:copyrightInfo
2010 The Authors. Clinical Microbiology and Infection; 2010 European Society of Clinical Microbiology and Infectious Diseases.
pubmed:issnType
Electronic
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
923-7
pubmed:meshHeading
pubmed-meshheading:21682806-Agriculture, pubmed-meshheading:21682806-Animals, pubmed-meshheading:21682806-Bacterial Typing Techniques, pubmed-meshheading:21682806-Carrier State, pubmed-meshheading:21682806-Cluster Analysis, pubmed-meshheading:21682806-Electrophoresis, Gel, Pulsed-Field, pubmed-meshheading:21682806-Genes, Bacterial, pubmed-meshheading:21682806-Genotype, pubmed-meshheading:21682806-Humans, pubmed-meshheading:21682806-Male, pubmed-meshheading:21682806-Methicillin-Resistant Staphylococcus aureus, pubmed-meshheading:21682806-Middle Aged, pubmed-meshheading:21682806-Molecular Epidemiology, pubmed-meshheading:21682806-Molecular Typing, pubmed-meshheading:21682806-Nasal Mucosa, pubmed-meshheading:21682806-Staphylococcal Skin Infections, pubmed-meshheading:21682806-Swine, pubmed-meshheading:21682806-Zoonoses
pubmed:year
2011
pubmed:articleTitle
Methicillin-resistant Staphylococcus aureus (MRSA) ST398 in a farmer with skin lesions and in pigs of his farm: clonal relationship and detection of lnu(A) gene.
pubmed:affiliation
Área Bioquímica y Biología Molecular, Universidad de La Rioja, Logroño, Spain.
pubmed:publicationType
Journal Article, Case Reports