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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2011-6-15
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pubmed:abstractText |
Apoptosis resistance of T-cells is considered an abnormality of immune pathways in Crohn's disease (CD). It has been previously shown that corticosteroids induce apoptosis of cells involved in inflammation. Thus, our aim was to assess the apoptosis of mononuclear cells and pro/antiinflammatory cytokines in the intestinal mucosa of patients with active CD, related to steroid response, and identify cellular and molecular factors that may predict this response to therapy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1536-4844
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pubmed:author |
pubmed-author:CarrascoAnnaA,
pubmed-author:DonovanMichaelM,
pubmed-author:EspinósJorge CJC,
pubmed-author:EsteveMariaM,
pubmed-author:Fernández-BañaresFernandoF,
pubmed-author:FornéMontserratM,
pubmed-author:GassullMiquel AMA,
pubmed-author:LorénVioletaV,
pubmed-author:LorasCarmeC,
pubmed-author:MañéJosepJ,
pubmed-author:MañosaMiriamM,
pubmed-author:MallolasJosefaJ,
pubmed-author:PedrosaElisabetE,
pubmed-author:PuigPereP,
pubmed-author:RosinachMercèM,
pubmed-author:SalasAntonioA,
pubmed-author:SantaolallaRebecaR,
pubmed-author:ViverJosep MJM
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pubmed:copyrightInfo |
Copyright © 2010 Crohn's & Colitis Foundation of America, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1490-500
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pubmed:meshHeading |
pubmed-meshheading:21674705-Adrenal Cortex Hormones,
pubmed-meshheading:21674705-Adult,
pubmed-meshheading:21674705-Apoptosis,
pubmed-meshheading:21674705-Blotting, Western,
pubmed-meshheading:21674705-Case-Control Studies,
pubmed-meshheading:21674705-Crohn Disease,
pubmed-meshheading:21674705-Drug Resistance,
pubmed-meshheading:21674705-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:21674705-Female,
pubmed-meshheading:21674705-Flow Cytometry,
pubmed-meshheading:21674705-Fluorescent Antibody Technique,
pubmed-meshheading:21674705-Follow-Up Studies,
pubmed-meshheading:21674705-Humans,
pubmed-meshheading:21674705-Immunoenzyme Techniques,
pubmed-meshheading:21674705-Immunophenotyping,
pubmed-meshheading:21674705-Immunoprecipitation,
pubmed-meshheading:21674705-Interleukin-10,
pubmed-meshheading:21674705-Lymphocytes,
pubmed-meshheading:21674705-Male,
pubmed-meshheading:21674705-Middle Aged,
pubmed-meshheading:21674705-Mucous Membrane,
pubmed-meshheading:21674705-Prognosis,
pubmed-meshheading:21674705-Prospective Studies,
pubmed-meshheading:21674705-RNA, Messenger,
pubmed-meshheading:21674705-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21674705-Survival Rate
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pubmed:year |
2011
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pubmed:articleTitle |
Apoptosis resistance of mucosal lymphocytes and IL-10 deficiency in patients with steroid-refractory Crohn's disease.
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pubmed:affiliation |
Department of Gastroenterology, Hospital Universitari Mútua de Terrassa, University of Barcelona, Research Foundation Mútua de Terrassa, Terrassa, Barcelona, Catalonia, Spain.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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