| pubmed-article:21672310 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21672310 | lifeskim:mentions | umls-concept:C0684249 | lld:lifeskim |
| pubmed-article:21672310 | lifeskim:mentions | umls-concept:C2750156 | lld:lifeskim |
| pubmed-article:21672310 | lifeskim:mentions | umls-concept:C1412323 | lld:lifeskim |
| pubmed-article:21672310 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21672310 | pubmed:dateCreated | 2011-6-15 | lld:pubmed |
| pubmed-article:21672310 | pubmed:abstractText | This prospective study explored the relationship between expression of AKR1B10 mRNA and various clinical parameters in non-small-cell lung cancer (NSCLC) in terms of its validation as a marker for NSCLC. Tumour tissue samples were collected from 229 patients with NSCLC. Tissue samples from adjacent non-malignant lung tissue (> 5 cm from the tumour) of 89 of these patients and samples from 20 patients with benign lung disease were used as controls. Quantitative reverse transcription- polymerase chain reaction showed significantly higher levels of AKR1B10 mRNA expression in NSCLC tumour tissue than in adjacent non-malignant lung tissue and benign lung tissue. Statistically significant factors for AKR1B10 mRNA over-expression were found to be male gender, smoking, squamous cell carcinoma and moderate or poor cell differentiation. It is concluded that AKR1B10 seems to have potential as a prognostic marker for NSCLC and warrants further investigation. | lld:pubmed |
| pubmed-article:21672310 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21672310 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21672310 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21672310 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21672310 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21672310 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21672310 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21672310 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21672310 | pubmed:issn | 1473-2300 | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:KimKK | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:KimH KHK | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:KassM AMA | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:LeeJJ | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:KitSS | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:ChoiY SYS | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:KimHH | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:KOKK | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:YoonS YSY | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:LEYE BEB | lld:pubmed |
| pubmed-article:21672310 | pubmed:author | pubmed-author:ShimY MYM | lld:pubmed |
| pubmed-article:21672310 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21672310 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:21672310 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21672310 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21672310 | pubmed:pagination | 78-85 | lld:pubmed |
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| pubmed-article:21672310 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21672310 | pubmed:articleTitle | AKR1B10 is associated with smoking and smoking-related non-small-cell lung cancer. | lld:pubmed |
| pubmed-article:21672310 | pubmed:affiliation | Cancer Research Centre, Centre for Clinical Research, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea. | lld:pubmed |
| pubmed-article:21672310 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21672310 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:57016 | entrezgene:pubmed | pubmed-article:21672310 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21672310 | lld:entrezgene |
