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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
25
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pubmed:dateCreated |
2011-6-28
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pubmed:abstractText |
Despite intensive investigation, how DNA methylation influences endothelial function remains poorly understood. We used methyl-CpG-binding domain protein 2 (MBD2), an interpreter for DNA methylome-encoded information, to dissect the impact of DNA methylation on endothelial function in both physiological and pathophysiological states.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:DongZhengZ,
pubmed-author:FultonDavid JDJ,
pubmed-author:RaoXiaoquanX,
pubmed-author:ShiHuidongH,
pubmed-author:WangCong-YiCY,
pubmed-author:WangDaowenD,
pubmed-author:WangMong-HengMH,
pubmed-author:YangPingP,
pubmed-author:YuQilinQ,
pubmed-author:ZhangShuS,
pubmed-author:ZhangYushanY,
pubmed-author:ZhongJixinJ
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pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2964-74
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pubmed:meshHeading |
pubmed-meshheading:21670230-Animals,
pubmed-meshheading:21670230-Apoptosis,
pubmed-meshheading:21670230-Cell Survival,
pubmed-meshheading:21670230-DNA Methylation,
pubmed-meshheading:21670230-DNA-Binding Proteins,
pubmed-meshheading:21670230-Endothelium, Vascular,
pubmed-meshheading:21670230-Epigenesis, Genetic,
pubmed-meshheading:21670230-Hindlimb,
pubmed-meshheading:21670230-Hydrogen Peroxide,
pubmed-meshheading:21670230-Ischemia,
pubmed-meshheading:21670230-Male,
pubmed-meshheading:21670230-Mice,
pubmed-meshheading:21670230-Mice, Knockout,
pubmed-meshheading:21670230-Models, Animal,
pubmed-meshheading:21670230-Neovascularization, Physiologic,
pubmed-meshheading:21670230-Nitric Oxide Synthase Type III,
pubmed-meshheading:21670230-Vascular Endothelial Growth Factor Receptor-2
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pubmed:year |
2011
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pubmed:articleTitle |
Loss of methyl-CpG-binding domain protein 2 enhances endothelial angiogenesis and protects mice against hind-limb ischemic injury.
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pubmed:affiliation |
Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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