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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2011-6-14
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pubmed:abstractText |
Increased liver iron stores may contribute to the progression of liver injury and fibrosis, and are associated with a higher risk of hepatocellular carcinoma development. Pre-transplant symptoms of iron overload in patients with liver cirrhosis are associated with higher risk of infectious and malignant complications in liver transplant recipients. HFE gene mutations may be involved in the pathogenesis of liver iron overload and influence the progression of chronic liver diseases of different origins. This study was designed to determine the prevalence of iron overload in relation to HFE gene mutations among Polish patients with liver cirrhosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1499-3872
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
270-5
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pubmed:meshHeading |
pubmed-meshheading:21669570-Adult,
pubmed-meshheading:21669570-Biological Markers,
pubmed-meshheading:21669570-Biopsy,
pubmed-meshheading:21669570-Carcinoma, Hepatocellular,
pubmed-meshheading:21669570-Case-Control Studies,
pubmed-meshheading:21669570-Chi-Square Distribution,
pubmed-meshheading:21669570-DNA Mutational Analysis,
pubmed-meshheading:21669570-Female,
pubmed-meshheading:21669570-Genetic Predisposition to Disease,
pubmed-meshheading:21669570-Hemochromatosis,
pubmed-meshheading:21669570-Histocompatibility Antigens Class I,
pubmed-meshheading:21669570-Homozygote,
pubmed-meshheading:21669570-Humans,
pubmed-meshheading:21669570-Iron Overload,
pubmed-meshheading:21669570-Liver Cirrhosis,
pubmed-meshheading:21669570-Liver Function Tests,
pubmed-meshheading:21669570-Liver Neoplasms,
pubmed-meshheading:21669570-Logistic Models,
pubmed-meshheading:21669570-Male,
pubmed-meshheading:21669570-Membrane Proteins,
pubmed-meshheading:21669570-Middle Aged,
pubmed-meshheading:21669570-Mutation,
pubmed-meshheading:21669570-Phenotype,
pubmed-meshheading:21669570-Poland,
pubmed-meshheading:21669570-Prevalence,
pubmed-meshheading:21669570-Risk Assessment,
pubmed-meshheading:21669570-Risk Factors
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pubmed:year |
2011
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pubmed:articleTitle |
Iron overload and HFE gene mutations in Polish patients with liver cirrhosis.
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pubmed:affiliation |
Department of Infectious Diseases, Medical University of Gdansk, ul. Smoluchowskiego 18, 80-218 Gdansk, Poland. ksikorska@gumed.edu.pl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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