Source:http://linkedlifedata.com/resource/pubmed/id/21668439
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2011-9-8
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pubmed:abstractText |
We report the case of a child who presented at 3 months of age with complex partial seizures, a linear facial nevus, and magnetic resonance imaging (MRI) showing delayed myelination and thickened cortex in the left temporal, parietal, and occipital regions. A repeat 3Tesla MRI scan with and without contrast at 6 months again showed cortical dysplasia of the left hemisphere. No other abnormalities were seen. A third scan at 3 years 6 months showed a 2.5 cm, round, hyperintense lesion on both T(2) and T(1) sequences. The lesion and surrounding dysplastic cortex were resected. Palmini grade IIA dysplasia and a ganglioglioma were diagnosed. These findings suggest that cellular components of cortical dysplasias have oncogenic potential.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1528-1167
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pubmed:author | |
pubmed:copyrightInfo |
Wiley Periodicals, Inc. © 2011 International League Against Epilepsy.
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e106-8
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pubmed:meshHeading |
pubmed-meshheading:21668439-Brain Neoplasms,
pubmed-meshheading:21668439-Female,
pubmed-meshheading:21668439-Ganglioglioma,
pubmed-meshheading:21668439-Glial Fibrillary Acidic Protein,
pubmed-meshheading:21668439-Humans,
pubmed-meshheading:21668439-Infant,
pubmed-meshheading:21668439-Magnetic Resonance Imaging,
pubmed-meshheading:21668439-Malformations of Cortical Development,
pubmed-meshheading:21668439-Phosphopyruvate Hydratase
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pubmed:year |
2011
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pubmed:articleTitle |
Ganglioglioma arising from dysplastic cortex.
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pubmed:affiliation |
Department of Pediatrics and Neurology, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. ortizgonzalez@email.chop.edu
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pubmed:publicationType |
Journal Article
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