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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1990-9-13
|
| pubmed:abstractText |
From 1979 through 1989, surgical resection was performed in 55 of 66 patients with carcinoma of the hepatic hilus after improving jaundice by percutaneous transhepatic biliary drainage (PTBD). Selective cholangiography through PTBD was done to define precisely the anatomical location--extent of the obstructing lesion in each segmental hepatic duct. Percutaneous transhepatic cholangioscopy was performed through the sinus tract of PTBD after replacing the drainage catheter with a 15 French catheter for superselective cholangiography and biopsy to make the definitive diagnosis of the histological extent of the tumor and any variation of each segmental hepatic duct that joins the hepatic hilus. In 46 (69.7%) of 66 patients, curative resection was possible. Forty-five of these underwent various types of hepatic segmentectomy with caudate lobectomy for a morbidity rate of 41.3% and an operative mortality rate of 6.4%. Fourteen (31.1%) advanced cases underwent combined resection of the portal vein together with hepatectomy. Microscopic tumor involvement in the caudate branches was confirmed in 44 of 45 patients who underwent caudate lobe resection. The 3-year survival rate for all 43 patients surviving the curative excision was 55.1% and the 5-year survival rate was 40.5%. All 11 patients who had an unresectable advanced tumor died within 9 months. Curative resection should be designed according to the preoperative findings of the extent of cancer in each segmental duct, and caudate lobe resection should be performed together with the smallest necessary hepatic segmentectomy possible.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0364-2313
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
535-43; discussion 544
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2166381-Adenoma, Bile Duct,
pubmed-meshheading:2166381-Adult,
pubmed-meshheading:2166381-Aged,
pubmed-meshheading:2166381-Bile Duct Neoplasms,
pubmed-meshheading:2166381-Bile Ducts, Intrahepatic,
pubmed-meshheading:2166381-Cholangiography,
pubmed-meshheading:2166381-Drainage,
pubmed-meshheading:2166381-Endoscopy,
pubmed-meshheading:2166381-Female,
pubmed-meshheading:2166381-Hepatectomy,
pubmed-meshheading:2166381-Humans,
pubmed-meshheading:2166381-Male,
pubmed-meshheading:2166381-Middle Aged,
pubmed-meshheading:2166381-Preoperative Care
|
| pubmed:articleTitle |
Hepatic segmentectomy with caudate lobe resection for bile duct carcinoma of the hepatic hilus.
|
| pubmed:affiliation |
First Department of Surgery, Nagoya University School of Medicine, Japan.
|
| pubmed:publicationType |
Journal Article
|