Source:http://linkedlifedata.com/resource/pubmed/id/21659769
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2011-6-10
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pubmed:abstractText |
Dyslipidemia is implicated as a risk factor for the development of atherosclerosis. Specifically triglyceride-rich lipoproteins and their lipolysis products are shown to be proinflammatory and proapoptosis in both in vivo and in vitro studies with endothelium. However, the role of triglyceride-rich lipoproteins in the progression of kidney diseases is not clear. Epidemiology studies demonstrated a correlation between renal disease and blood lipids. Recent evidence suggests that the mechanism may involve cellular uptake of lipid and de novo lipogenesis. Further studies are needed to establish the relevance of these mechanistic studies in human pathophysiology.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1662-2782
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
170
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-71
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pubmed:meshHeading |
pubmed-meshheading:21659769-Animals,
pubmed-meshheading:21659769-Disease Models, Animal,
pubmed-meshheading:21659769-Humans,
pubmed-meshheading:21659769-Hypertriglyceridemia,
pubmed-meshheading:21659769-Kidney Diseases,
pubmed-meshheading:21659769-Lipoproteins,
pubmed-meshheading:21659769-Mice,
pubmed-meshheading:21659769-Triglycerides
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pubmed:year |
2011
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pubmed:articleTitle |
Role of triglyceride-rich lipoproteins in renal injury.
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pubmed:affiliation |
Division of Cardiovascular Medicine, University of California Davis School of Medicine, Davis, Calif 95616, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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