| pubmed-article:2165909 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C0055633 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C0204727 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C0445223 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C1552599 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C0439836 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C1704787 | lld:lifeskim |
| pubmed-article:2165909 | lifeskim:mentions | umls-concept:C1519667 | lld:lifeskim |
| pubmed-article:2165909 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2165909 | pubmed:dateCreated | 1990-9-10 | lld:pubmed |
| pubmed-article:2165909 | pubmed:abstractText | A protein with pancreastatin-like immunoreactivity has been isolated and purified from liver metastasis of a patient with insulinoma. NH2-terminal residue analysis, in conjunction with the use of antibodies that are specific for the C-terminal amide peptide of porcine pancreastatin, identified this protein as a 186-amino-acid protein corresponding to human chromogranin A-116-301 (the fragment corresponding to the positions from 116 to 301 of human chromogranin A). Digestion of this protein with trypsin yielded a 48-amino-acid peptide with the retention of full pancreastatin activity. Serum from patient with insulinoma contains a peptide specie(s) that comigrates with the 48-amino-acid pancreastatin, suggesting that this peptide might be a physiologically important circulation form of pancreastatin in humans. A sensitive radioimmunoassay was established using antibody developed against a synthetic 29-amino-acid peptide amide of pancreastatin. Immunocytochemical staining revealed that a major population of human pancreatic islet cells were immunoreactive to the antiserum but with varying intensity of staining. Pancreastatin-like immunoreactivity was not observed in exocrine acinar cells. | lld:pubmed |
| pubmed-article:2165909 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2165909 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2165909 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2165909 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:2165909 | pubmed:issn | 0014-2956 | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:OnoYY | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:YajimaHH | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:OhtaMM | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:FujiiNN | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:FunakoshiAA | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:MiyasakiSS | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:YoshizawaKK | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:TateishiKK | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:JimiAA | lld:pubmed |
| pubmed-article:2165909 | pubmed:author | pubmed-author:TamamuraHH | lld:pubmed |
| pubmed-article:2165909 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2165909 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:2165909 | pubmed:volume | 191 | lld:pubmed |
| pubmed-article:2165909 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2165909 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:2165909 | pubmed:pagination | 33-9 | lld:pubmed |
| pubmed-article:2165909 | pubmed:dateRevised | 2007-7-23 | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:meshHeading | pubmed-meshheading:2165909-... | lld:pubmed |
| pubmed-article:2165909 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2165909 | pubmed:articleTitle | Isolation and characterization of a tumor-derived human protein related to chromogranin A and its in vitro conversion to human pancreastatin-48. | lld:pubmed |
| pubmed-article:2165909 | pubmed:affiliation | Faculty of Pharmaceutical Sciences, Kyoto University, Japan. | lld:pubmed |
| pubmed-article:2165909 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:1113 | entrezgene:pubmed | pubmed-article:2165909 | lld:entrezgene |
