Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-6-9
pubmed:abstractText
The study included a total of 28 cases of urothelial carcinomas, which were analyzed histopathologically and immunohistochemically using anti-human p16, c-erbB2 and Ki67 antibodies and the LSAB/HRP work system. Histopathological analysis revealed the presence of urothelial carcinomas with different degrees of differentiation and invasion in the lamina propria or muscularis propria. The immunostain for p16, c-erbB2 and Ki67 was present at the nuclear and cytoplasmic level, respectively at membrane and nuclear level. Immunoreactions had quantified values, which were statistically correlated with the degree of differentiation in case of c-erbB2 or depth of invasion for p16. Tumor activity status and the risk of progression of bladder urothelial carcinomas can be assessed objectively using the antibody panel consisting of p16, c-erbB2 and Ki67.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1220-0522
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
653-8
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
P16, c-erbB2 and Ki67 immunoexpression in urothelial carcinomas of the bladder.
pubmed:affiliation
Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania. astepan76@yahoo.com
pubmed:publicationType
Journal Article