Linked Life Data

2165163

Source:http://linkedlifedata.com/resource/pubmed/id/2165163

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1990-8-30
pubmed:abstractText
A series of acyclic and C-acyclic 7-deazapurine nucleosides have been synthesized and tested for antiviral activity. Reaction of the sodium salt of 2-amino-3,4-bis(aminocarbonyl)-5-(methylthio)pyrrole (6) with an appropriate electrophile gave pyrrole nucleosides which served as common intermediates to both the 7-deazaadenosine and the 7-deazaguanosine series. Several of these 5- and 5,6-substituted pyrrolo[2,3-d]pyrimidine nucleosides have shown activity against HIV virus in preliminary in vitro screens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-2623
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2162-73
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Synthesis and antiviral activity of some acyclic and C-acyclic pyrrolo[2,3-d]pyrimidine nucleoside analogues.
pubmed:affiliation
Department of Chemistry, McGill University, Montreal, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't