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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-6-8
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pubmed:abstractText |
Safe pharmacotherapy and prevention of arrhythmia is an urgent problem of modern cardiology. Essential micronutrients such as omega-3 polyunsaturated fatty acids (-3 PUF-) significantly contribute to the metabolic processes in cardiomyocytes and cardiac conduction system. This article presents a systematic analysis of anti-arrhythmic effects of omega-3 PUFA and of standardized ethyl esters of omega-3 PUFA. The currently available data indicate two fundamentally different molecular mechanisms of anti-arrhythmic effects: "slow" and "fast" types. Formulation of fundamental prospects of bioinformatic studies of molecular effects of anti-arrhythmic action of omega-3 PUF-s is presented.
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pubmed:language |
rus
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Arachidonic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Cardiovascular Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochromes,
http://linkedlifedata.com/resource/pubmed/chemical/Docosahexaenoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Eicosapentaenoic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Omega-3,
http://linkedlifedata.com/resource/pubmed/chemical/Ion Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Micronutrients,
http://linkedlifedata.com/resource/pubmed/chemical/Omacor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Eicosanoid,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prostaglandin
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pubmed:status |
MEDLINE
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pubmed:issn |
0022-9040
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-49
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pubmed:meshHeading |
pubmed-meshheading:21649594-Arachidonic Acid,
pubmed-meshheading:21649594-Arrhythmias, Cardiac,
pubmed-meshheading:21649594-Biotransformation,
pubmed-meshheading:21649594-Cardiovascular Agents,
pubmed-meshheading:21649594-Clinical Trials as Topic,
pubmed-meshheading:21649594-Cytochromes,
pubmed-meshheading:21649594-Docosahexaenoic Acids,
pubmed-meshheading:21649594-Drug Combinations,
pubmed-meshheading:21649594-Eicosapentaenoic Acid,
pubmed-meshheading:21649594-Fatty Acids, Omega-3,
pubmed-meshheading:21649594-Heart Conduction System,
pubmed-meshheading:21649594-Humans,
pubmed-meshheading:21649594-Ion Channels,
pubmed-meshheading:21649594-Micronutrients,
pubmed-meshheading:21649594-Myocytes, Cardiac,
pubmed-meshheading:21649594-Receptors, Eicosanoid,
pubmed-meshheading:21649594-Receptors, Prostaglandin
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pubmed:year |
2011
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pubmed:articleTitle |
[Systematic analysis of molecular mechanisms of action of omega-3 polyunsaturated fatty acids on arrhythmia].
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pubmed:publicationType |
Journal Article,
English Abstract,
Meta-Analysis
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