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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1990-8-30
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pubmed:abstractText |
In late 1988, a cross-sectional study of 1715 adult medical patients hospitalized in Abidjan, Côte d'Ivoire, west Africa, showed an overall prevalence of HIV infection of 46% in men and 28% in women. On the basis of specific testing by whole virus enzyme-linked immunosorbent assay (ELISA), Western blot and synthetic peptide ELISA, HIV-1 infection was found in 25%, HIV-2 infection in 4%, and reactivity to both viruses in 11% of male and female patients combined. People infected with HIV-2, as well as those who were reactive to both HIV-1 and HIV-2, had a frequency of AIDS-associated symptoms and signs similar to that in HIV-1-infected patients, and significantly greater than that in seronegative patients. The significance of dual reactivity, and the natural history and disease spectrum of HIV-2 infection, require further study. Synthetic peptide ELISA is valuable for specific serodiagnosis of HIV-1 and HIV-2 infections. Advanced HIV-2 infection in hospitalized patients in Abidjan is associated with the same symptoms and signs as HIV-1 infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0269-9370
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
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pubmed:pagination |
443-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2164821-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2164821-Adolescent,
pubmed-meshheading:2164821-Adult,
pubmed-meshheading:2164821-Cote d'Ivoire,
pubmed-meshheading:2164821-Female,
pubmed-meshheading:2164821-HIV-1,
pubmed-meshheading:2164821-HIV-2,
pubmed-meshheading:2164821-Humans,
pubmed-meshheading:2164821-Male,
pubmed-meshheading:2164821-Middle Aged,
pubmed-meshheading:2164821-Prevalence
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pubmed:year |
1990
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pubmed:articleTitle |
A comparison of HIV-1 and HIV-2 infections in hospitalized patients in Abidjan, Côte d'Ivoire.
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pubmed:affiliation |
Projet RETRO-CI, Abidjan, Côte d'Ivoire.
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pubmed:publicationType |
Journal Article,
Comparative Study
|