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rdf:type |
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lifeskim:mentions |
umls-concept:C0024880,
umls-concept:C0205263,
umls-concept:C0591833,
umls-concept:C1335874,
umls-concept:C1337092,
umls-concept:C1514873,
umls-concept:C1515670,
umls-concept:C1522558,
umls-concept:C1546857,
umls-concept:C1556066,
umls-concept:C1619636,
umls-concept:C1705079
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pubmed:dateCreated |
2011-6-7
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pubmed:abstractText |
Mast cells are immunocompetent cells that are found in almost all tissues and function as sentinels of immune responses. Recently, it has been shown that mast cells play significant roles in innate immune responses. However, it is still largely unknown whether signal transducers and activators of transcription 4 (STAT4), one of the STAT proteins under type I IFN signaling, is involved in type I IFN-mediated gene expression in mast cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Ccl2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-beta,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-3,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-kit,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, IgE,
http://linkedlifedata.com/resource/pubmed/chemical/STAT1 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT4 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Stat1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Stat4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/beta-N-Acetylhexosaminidases
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0097
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
155 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-6
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pubmed:meshHeading |
pubmed-meshheading:21646799-Animals,
pubmed-meshheading:21646799-Cell Degranulation,
pubmed-meshheading:21646799-Cell Proliferation,
pubmed-meshheading:21646799-Chemokine CCL2,
pubmed-meshheading:21646799-Gene Expression,
pubmed-meshheading:21646799-Gene Expression Regulation,
pubmed-meshheading:21646799-Interferon-beta,
pubmed-meshheading:21646799-Interleukin-3,
pubmed-meshheading:21646799-Mast Cells,
pubmed-meshheading:21646799-Mice,
pubmed-meshheading:21646799-Mice, Inbred C57BL,
pubmed-meshheading:21646799-Mice, Knockout,
pubmed-meshheading:21646799-Phosphorylation,
pubmed-meshheading:21646799-Proto-Oncogene Proteins c-kit,
pubmed-meshheading:21646799-Receptors, IgE,
pubmed-meshheading:21646799-STAT1 Transcription Factor,
pubmed-meshheading:21646799-STAT4 Transcription Factor,
pubmed-meshheading:21646799-beta-N-Acetylhexosaminidases
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pubmed:year |
2011
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pubmed:articleTitle |
STAT4 is required for IFN-?-induced MCP-1 mRNA expression in murine mast cells.
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pubmed:affiliation |
Department of Molecular Genetics, Graduate School of Medicine, Chiba University, Chiba, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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