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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2011-7-26
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pubmed:abstractText |
In diabetes, when glucose consumption is restricted, the heart adapts to use fatty acid (FA) exclusively. The majority of FA provided to the heart comes from the breakdown of circulating triglyceride (TG), a process catalyzed by lipoprotein lipase (LPL) located at the vascular lumen. The objective of the current study was to determine the mechanisms behind LPL processing and breakdown after moderate and severe diabetes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1939-327X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2041-50
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pubmed:meshHeading |
pubmed-meshheading:21646389-Angiopoietins,
pubmed-meshheading:21646389-Animals,
pubmed-meshheading:21646389-Calnexin,
pubmed-meshheading:21646389-Diabetes Mellitus, Experimental,
pubmed-meshheading:21646389-Diazoxide,
pubmed-meshheading:21646389-Fatty Acids, Nonesterified,
pubmed-meshheading:21646389-Hyperglycemia,
pubmed-meshheading:21646389-Lipoprotein Lipase,
pubmed-meshheading:21646389-Male,
pubmed-meshheading:21646389-Myocardium,
pubmed-meshheading:21646389-Protein Multimerization,
pubmed-meshheading:21646389-Rats,
pubmed-meshheading:21646389-Rats, Wistar,
pubmed-meshheading:21646389-Streptozocin
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pubmed:year |
2011
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pubmed:articleTitle |
Severity of diabetes governs vascular lipoprotein lipase by affecting enzyme dimerization and disassembly.
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pubmed:affiliation |
Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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