Linked Life Data

21645679

Source:http://linkedlifedata.com/resource/pubmed/id/21645679

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2011-6-7
pubmed:abstractText
A highly sensitive electrochemical immunosensor based on combination of chitosan (CHIT) and coral-shaped AuNPs (C-AuNPs) to form an immobilization matrix has been developed using human IgG as a model analyte. The inorganic-organic hybrid film with abundant adsorbing sites and large surface area can reserve the biocompatibility of the biomaterials which greatly increase loading amounts of assembling, thus, significantly improves the performance of biosensing. The morphology is studied by scanning electron microscopy (SEM). Under the optimized experimental conditions, the immunosensor exhibits excellent performance (e.g., a detection limit of 5 pmol L(-1), a linear dynamic range of 3 orders of magnitude, high specificity). This possibly makes it an attractive platform for the direct immunoassay of human IgG or other biomolecules.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1873-3573
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
117-22
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
A highly sensitive electrochemical immunosensor based on coral-shaped AuNPs with CHITs inorganic-organic hybrid film.
pubmed:affiliation
State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, PR China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't