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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2011-7-1
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pubmed:abstractText |
It is of growing interest to develop novel approaches to initiate differentiation of mesenchymal stem cells (MSCs) into cardiomyocytes. The purpose of this investigation was to determine if Sphingosine-1-phosphate (S1P), a native circulating bioactive lipid metabolite, plays a role in differentiation of human umbilical cord mesenchymal stem cells (HUMSCs) into cardiomyocytes. We also developed an engineered cell sheet from these HUMSCs derived cardiomyocytes by using a temperature-responsive polymer, poly(N-isopropylacrylamide) (PIPAAm) cell sheet technology.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-12699668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-15147820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-16529415,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-17236213,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-17690177,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-18006453,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-18393631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-18852872,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-19228106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-19535686,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21645412-20584786
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0127
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37
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pubmed:meshHeading |
pubmed-meshheading:21645412-Acrylamides,
pubmed-meshheading:21645412-Actinin,
pubmed-meshheading:21645412-Cell Culture Techniques,
pubmed-meshheading:21645412-Cell Differentiation,
pubmed-meshheading:21645412-Cells, Cultured,
pubmed-meshheading:21645412-Humans,
pubmed-meshheading:21645412-Lysophospholipids,
pubmed-meshheading:21645412-Mesenchymal Stem Cells,
pubmed-meshheading:21645412-Myocytes, Cardiac,
pubmed-meshheading:21645412-Myosin Heavy Chains,
pubmed-meshheading:21645412-Polymers,
pubmed-meshheading:21645412-Sphingosine,
pubmed-meshheading:21645412-Tissue Engineering,
pubmed-meshheading:21645412-Umbilical Cord
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pubmed:year |
2011
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pubmed:articleTitle |
Sphingosine-1-phosphate promotes the differentiation of human umbilical cord mesenchymal stem cells into cardiomyocytes under the designated culturing conditions.
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pubmed:affiliation |
Department of Neurology, Affiliated Hospital, Hainan Medical College, Haikou, P.R. China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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