Linked Life Data

2164500

Source:http://linkedlifedata.com/resource/pubmed/id/2164500

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
97
pubmed:dateCreated
1990-8-21
pubmed:abstractText
A case-referent study has been carried out to test the hypothesis that silica-exposed ceramic workers have an increased risk of lung cancer. Next-of-kin interviews were conducted for 72 lung cancer cases and 319 referents, all deceased, to collect work histories and smoking habits. The diagnosis of silicosis was ascertained by checking the individual files of cases of silicosis where compensation had been received. It was found that, after controlling for age, period of death and smoking, workers in the ceramic industry had a higher lung cancer risk than those in other occupations in which there was no exposure to silica (Mantel-Haenszel rate ratio = 2.0; 95% confidence interval (CI) = 1.1-3.5). This increased risk was mainly due to a rate ratio of 3.9 (95% CI = 1.8-8.3) for silicotic individuals, while for non-silicotic ceramic workers it was only 1.4 (95% CI = 0.7-2.8). Exposure to other carcinogens in the workplace seems not to play any role in the development of lung cancer. Furthermore, the data do not suggest an increased risk for silicotic non-smokers. The results of the study tend to confirm previous evidence of an excess risk among silicotic subjects and points to a possible etiological role of the silicotic process itself in lung cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5038
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
A case-referent study on lung cancer mortality among ceramic workers.
pubmed:affiliation
Epidemiological Unit, Latium Regional Health Authority, Rome, Italy.
pubmed:publicationType
Journal Article