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pubmed-article:21636950pubmed:abstractTextReverse cholesterol transport (RCT) is a critical mechanism for the anti-atherogenic property of HDL. The inhibitory effect of the sulfonylurea agent (SUA) glibenclamide on ATP binding-cassette transporter (ABC) A1 may decrease HDL function but it remains unclear whether it attenuates RCT in vivo. We therefore investigated how the SUAs glibenclamide and glimepiride affected the functionality of ABCA1/ABCG1 and scavenger receptor class B type I (SR-BI) expression in macrophages in vitro and overall RCT in vivo.lld:pubmed
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pubmed-article:21636950pubmed:articleTitleEffect of sulfonylurea agents on reverse cholesterol transport in vitro and vivo.lld:pubmed
pubmed-article:21636950pubmed:affiliationDivision of Anti-aging, Department of Internal Medicine, National Defense Medical College, Saitama, Japan.lld:pubmed
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