21636598

Source:http://linkedlifedata.com/resource/pubmed/id/21636598

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0000956, umls-concept:C0002045, umls-concept:C0024501, umls-concept:C0031444, umls-concept:C0178602, umls-concept:C0815172, umls-concept:C1511726, umls-concept:C1708715, umls-concept:C2346689
pubmed:issue	15
pubmed:dateCreated	2011-8-2
pubmed:abstractText	Polymorphisms in CYP2C9 and VKORC1 influence patients' phenprocoumon (PHE) and acenocoumarol (ACE) dose requirements. To provide physicians with tools to estimate the patient's individual dose, we aimed to develop algorithms for PHE and ACE.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8006263
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Acenocoumarol, http://linkedlifedata.com/resource/pubmed/chemical/Anticoagulants, http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases, http://linkedlifedata.com/resource/pubmed/chemical/CYP2C9 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases, http://linkedlifedata.com/resource/pubmed/chemical/Phenprocoumon, http://linkedlifedata.com/resource/pubmed/chemical/vitamin K epoxidase
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1522-9645
pubmed:author	pubmed-author:EU-PACT Study Group, pubmed-author:Maitland-van der ZeeAnke-HilseAH, pubmed-author:RosendaalFrits RFR, pubmed-author:SchalekampTomT, pubmed-author:VerhoefTalitha ITI, pubmed-author:WesselsJudith A MJA, pubmed-author:de BoerAnthoniusA, pubmed-author:le CessieSaskiaS, pubmed-author:van MeegenErikE, pubmed-author:van SchieRianne M FRM, pubmed-author:van der MeerFelix J MFJ
pubmed:issnType	Electronic
pubmed:volume	32
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1909-17
pubmed:meshHeading	pubmed-meshheading:21636598-Acenocoumarol, pubmed-meshheading:21636598-Administration, Oral, pubmed-meshheading:21636598-Adult, pubmed-meshheading:21636598-Aged, pubmed-meshheading:21636598-Algorithms, pubmed-meshheading:21636598-Anticoagulants, pubmed-meshheading:21636598-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:21636598-Body Height, pubmed-meshheading:21636598-Body Weight, pubmed-meshheading:21636598-Drug Dosage Calculations, pubmed-meshheading:21636598-Female, pubmed-meshheading:21636598-Genotype, pubmed-meshheading:21636598-Humans, pubmed-meshheading:21636598-International Normalized Ratio, pubmed-meshheading:21636598-Male, pubmed-meshheading:21636598-Middle Aged, pubmed-meshheading:21636598-Mixed Function Oxygenases, pubmed-meshheading:21636598-Pharmacogenetics, pubmed-meshheading:21636598-Phenprocoumon, pubmed-meshheading:21636598-Polymorphism, Genetic
pubmed:year	2011
pubmed:articleTitle	Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data.
pubmed:affiliation	Study coordinating Centre, Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80 082, 3508 TB Utrecht, The Netherlands.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Multicenter Study, Validation Studies