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pubmed-article:21633323pubmed:abstractTextIn pediatric onset of Crohn's disease (CD), corticosteroid dependency (approximately 40%) and resistance (approximately 10%) are significant clinical problems. Given the known effects of the glucocorticoid receptor (GR/NR3C1) gene in corticosteroid metabolism, we investigated whether variation in the gene was associated with corticosteroid response.lld:pubmed
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pubmed-article:21633323pubmed:articleTitleVariation in the glucocorticoid receptor gene (NR3C1) may be associated with corticosteroid dependency and resistance in children with Crohn's disease.lld:pubmed
pubmed-article:21633323pubmed:affiliationResearch Centre, Sainte-Justine Hospital, Montreal, Quebec, Canada.lld:pubmed
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