Linked Life Data

2162981

Source:http://linkedlifedata.com/resource/pubmed/id/2162981

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-8-1
pubmed:abstractText
Dual photon absorptiometry (DPA) was used to determine the in vivo bone mineral content (BMC) and bone mineral density of lumbar vertebrae (L2-4) in feral adult male cynomolgus macaques (Macaca fascicularis, n = 20). Following in vivo DPA scans, all animals were euthanized and the lumbar spine segment excised. The excised lumbar vertebrae, plus spinal cord, were formalin-fixed and measured three times by ex vivo DPA. The first ex vivo scan matched the monkey's own in vivo soft tissue beam attenuation ratio (Rs, ranging from 1.38 to 1.45). The second ex vivo scan was made creating a constant obese-like condition (Rs = 1.38), and the third creating a constant lean-like condition (Rs = 1.45). All scans were taken at a 1.0 mm point resolution, 1.0 mm line spacing, a 6 cm width, and a scan speed of 5 mm/sec. The second lumbar vertebra (L2) was ashed and the ash weight was compared to the measured L2BMC of the in vivo and ex vivo DPA analyses. Noninvasive in vivo DPA proved to be adequate in measuring the lumbar bone mineral content in male cynomolgus macaques. Ex vivo DPA at a high and constant Rs value of 1.45 provided for the best accuracy of formalin-fixed wet bone tissue when compared to the bone ash weight.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0023-6764
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
266-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Accuracy and reproducibility of lumbar bone mineral status determined by dual photon absorptiometry in live male cynomolgus macaques (Macaca fascicularis).
pubmed:affiliation
Department of Comparative Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27103.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.