Source:http://linkedlifedata.com/resource/pubmed/id/21627384
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2011-6-1
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pubmed:abstractText |
To evaluate the relationship between physiological, reproductive factors and risk of breast cancer, we conducted a case-control study with 669 cases and 682 population-based controls in Jiangsu Province of China. A structured questionnaire was used to elicit detailed information. All subjects completed an in-person interview. Unconditional logistic regression analysis was performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) as measures of risk for breast cancer. The results have revealed that there was an increasing risk of breast cancer, include early age at menarche(? 13 year), late age at menopause(< 50 year) and older age at first pregnancy (? 30 year). Breastfeeding was associated significantly with a reduced risk of breast cancer. Women who had history of breastfeeding were at significantly decreased OR (0.44, 95%CI: 0.27-0.73). The protective effects of breastfeeding for breast cancer seemed greater for women who had extended duration of breastfeeding during their lifetime (p for linear trend: 0.0095). These results suggested that physiological and reproductive factors may play important roles in the development of breast cancer among Jiangsu' women of China.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1513-7368
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
787-90
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pubmed:meshHeading |
pubmed-meshheading:21627384-Adult,
pubmed-meshheading:21627384-Age Factors,
pubmed-meshheading:21627384-Body Mass Index,
pubmed-meshheading:21627384-Breast Feeding,
pubmed-meshheading:21627384-Breast Neoplasms,
pubmed-meshheading:21627384-Case-Control Studies,
pubmed-meshheading:21627384-China,
pubmed-meshheading:21627384-Female,
pubmed-meshheading:21627384-Follow-Up Studies,
pubmed-meshheading:21627384-Humans,
pubmed-meshheading:21627384-Menopause,
pubmed-meshheading:21627384-Middle Aged,
pubmed-meshheading:21627384-Parity,
pubmed-meshheading:21627384-Pregnancy,
pubmed-meshheading:21627384-Questionnaires,
pubmed-meshheading:21627384-Reproductive History,
pubmed-meshheading:21627384-Risk Factors
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pubmed:year |
2011
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pubmed:articleTitle |
Physiological, reproductive factors and breast cancer risk in Jiangsu province of China.
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pubmed:affiliation |
Division of Epidemiology, Jiangsu Province Institute of Cancer Research, Nanjing, China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial
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