Source:http://linkedlifedata.com/resource/pubmed/id/21623870
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2011-7-27
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pubmed:abstractText |
Primary cutaneous extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT) represents a monoclonal B-cell neoplasm that typically presents with papules, plaques or nodules. We describe a patient with a primary cutaneous MALT lymphoma with unusual clinical features and an unusual immunophenotype. Conventional microscopy together with immunohistochemistry and in-situ hybridization showed the presence of lymphoma in normal-appearing and minimally erythematous skin as well as in clinically involved skin. Furthermore, at least two distinct clones were shown, one of which had ?-light chain restriction, and the other of which had ?-light chain restriction. This case represents a newly described clinical appearance of primary cutaneous MZL and shows that some patients may have more than one neoplastic clone.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1600-0560
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pubmed:author | |
pubmed:copyrightInfo |
2011 John Wiley & Sons A/S.
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
724-30
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pubmed:meshHeading |
pubmed-meshheading:21623870-Adult,
pubmed-meshheading:21623870-Humans,
pubmed-meshheading:21623870-Immunoglobulin kappa-Chains,
pubmed-meshheading:21623870-Immunoglobulin lambda-Chains,
pubmed-meshheading:21623870-Immunohistochemistry,
pubmed-meshheading:21623870-Lymphoma, B-Cell, Marginal Zone,
pubmed-meshheading:21623870-Male,
pubmed-meshheading:21623870-Neoplasm Proteins,
pubmed-meshheading:21623870-Skin,
pubmed-meshheading:21623870-Skin Neoplasms
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pubmed:year |
2011
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pubmed:articleTitle |
Primary cutaneous marginal zone lymphoma with subclinical cutaneous involvement and biclonality.
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pubmed:affiliation |
Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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