rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2011-9-19
|
pubmed:abstractText |
Genetic association studies of schizophrenia typically utilize diagnostic status as the trait of interest. Among Indian schizophrenia (SZ) participants, we evaluated genetic associations (selected single nucleotide polymorphisms (SNPs) associated with SZ) with selected indices of severity and symptom pattern. Ordinal logistic regression enabled us to analyze variables with multiple categories as outcome variables, while incorporating key demographic variables; this form of analysis may be useful in future genetic association studies. No significant associations were detected following corrections for multiple comparisons.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0165-1781
|
pubmed:author |
pubmed-author:BhatiaTriptishT,
pubmed-author:ChandraAbhaA,
pubmed-author:DeshpandeSmita NSN,
pubmed-author:GaubaDeepakD,
pubmed-author:KodavaliChowdariC,
pubmed-author:MishraN NNN,
pubmed-author:NimgaonkarVishwajit LVL,
pubmed-author:SemwalPrachiP,
pubmed-author:SharmaVikash RanjanVR,
pubmed-author:ThelmaB KBK,
pubmed-author:ThomasPramodP,
pubmed-author:WoodJoelJ
|
pubmed:copyrightInfo |
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
|
pubmed:issnType |
Print
|
pubmed:day |
30
|
pubmed:volume |
189
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
321-3
|
pubmed:meshHeading |
pubmed-meshheading:21621274-Adult,
pubmed-meshheading:21621274-Female,
pubmed-meshheading:21621274-Genetic Predisposition to Disease,
pubmed-meshheading:21621274-Genome-Wide Association Study,
pubmed-meshheading:21621274-Humans,
pubmed-meshheading:21621274-India,
pubmed-meshheading:21621274-Logistic Models,
pubmed-meshheading:21621274-Male,
pubmed-meshheading:21621274-Polymorphism, Single Nucleotide,
pubmed-meshheading:21621274-Schizophrenia,
pubmed-meshheading:21621274-Young Adult
|
pubmed:year |
2011
|
pubmed:articleTitle |
Clinical and genetic correlates of severity in schizophrenia in India: an ordinal logistic regression approach.
|
pubmed:affiliation |
Dr RML Hospital, New Delhi, India.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|