Source:http://linkedlifedata.com/resource/pubmed/id/21620450
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-7-18
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pubmed:abstractText |
Over 90% of all cervical adenocarcinoma are caused by a transforming infection with a high-risk type human papillomavirus (hrHPV). Previous studies demonstrated that the association between hrHPV positivity and cervical clear-cell adenocarcinoma (CCAC) varies between 0% and 100%. As approximately 60% of all CCAC are associated with intra-uterine diethylstilbestrol (DES) exposure, we determined in a cohort of both DES-exposed and DES-unexposed women the prevalence of hrHPV infections, and the potential etiological role of hrHPV by additional analysis of p16INK4a and p53 expression.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1095-6859
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
122
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-302
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pubmed:meshHeading |
pubmed-meshheading:21620450-Adenocarcinoma, Clear Cell,
pubmed-meshheading:21620450-Adolescent,
pubmed-meshheading:21620450-Adult,
pubmed-meshheading:21620450-Diethylstilbestrol,
pubmed-meshheading:21620450-Female,
pubmed-meshheading:21620450-Humans,
pubmed-meshheading:21620450-Immunohistochemistry,
pubmed-meshheading:21620450-Middle Aged,
pubmed-meshheading:21620450-Neoplasm Proteins,
pubmed-meshheading:21620450-Papillomaviridae,
pubmed-meshheading:21620450-Polymerase Chain Reaction,
pubmed-meshheading:21620450-Pregnancy,
pubmed-meshheading:21620450-Prenatal Exposure Delayed Effects,
pubmed-meshheading:21620450-Risk,
pubmed-meshheading:21620450-Tumor Suppressor Protein p53,
pubmed-meshheading:21620450-Uterine Cervical Neoplasms
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pubmed:year |
2011
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pubmed:articleTitle |
High-risk human papillomavirus seems not involved in DES-related and of limited importance in nonDES related clear-cell carcinoma of the cervix.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands. m.kocken@erasmusmc.nl
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pubmed:publicationType |
Journal Article
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