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rdf:type |
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lifeskim:mentions |
umls-concept:C0007137,
umls-concept:C0007600,
umls-concept:C0034634,
umls-concept:C0162574,
umls-concept:C0597357,
umls-concept:C0600210,
umls-concept:C1257890,
umls-concept:C1280500,
umls-concept:C1366622,
umls-concept:C1518174,
umls-concept:C1704675
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pubmed:issue |
2
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pubmed:dateCreated |
2011-5-27
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pubmed:abstractText |
The receptor for advanced glycation end products (RAGE) is a multiligand cell surface receptor of the immunoglobulin superfamily and a newly recognized invasion-related gene. High mobility group box-1 (HMGB-1) is a 30-kD protein binding to RAGE and acting as a transcription-factor-like protein that regulates the expression of several genes. In this study, the interaction effect between RAGE and HMGB-1 on the migration of SCC7 cells was investigated along with the inhibitory effect of the drug nifedipine on this interaction effect.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0300-8916
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
196-202
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pubmed:meshHeading |
pubmed-meshheading:21617715-Antineoplastic Agents,
pubmed-meshheading:21617715-Blotting, Western,
pubmed-meshheading:21617715-Carcinoma, Squamous Cell,
pubmed-meshheading:21617715-Cell Line, Tumor,
pubmed-meshheading:21617715-Cell Migration Assays,
pubmed-meshheading:21617715-Cell Movement,
pubmed-meshheading:21617715-Dose-Response Relationship, Drug,
pubmed-meshheading:21617715-HMGB1 Protein,
pubmed-meshheading:21617715-Head and Neck Neoplasms,
pubmed-meshheading:21617715-Humans,
pubmed-meshheading:21617715-Immunohistochemistry,
pubmed-meshheading:21617715-Nifedipine,
pubmed-meshheading:21617715-Receptors, Immunologic,
pubmed-meshheading:21617715-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:articleTitle |
Interaction effect between the receptor for advanced glycation end products (RAGE) and high-mobility group box-1 (HMGB-1) for the migration of a squamous cell carcinoma cell line.
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pubmed:affiliation |
Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Medical Center, Ansan City, Gyunggi-Do, Korea.
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pubmed:publicationType |
Journal Article
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