Linked Life Data

21613800

Source:http://linkedlifedata.com/resource/pubmed/id/21613800

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-6-24
pubmed:abstractText
Gastrointestinal stromal tumor (GIST) is characterized by KIT or PDGFRA gene mutation. Although chromosomal losses of 22q are frequent in GIST, it is unclear which tumor suppressor genes might be inactivated in association with such losses. The INI1 gene, located at 22q11.23, is a tumor suppressor gene that is frequently altered in malignant rhabdoid tumor.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1423-0291
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 S. Karger AG, Basel.
pubmed:issnType
Electronic
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
132-9
pubmed:meshHeading
pubmed-meshheading:21613800-Adult, pubmed-meshheading:21613800-Aged, pubmed-meshheading:21613800-Aged, 80 and over, pubmed-meshheading:21613800-Chromosomal Proteins, Non-Histone, pubmed-meshheading:21613800-Chromosomes, Human, Pair 22, pubmed-meshheading:21613800-Cyclin D1, pubmed-meshheading:21613800-Cyclin-Dependent Kinase Inhibitor p16, pubmed-meshheading:21613800-DNA Mutational Analysis, pubmed-meshheading:21613800-DNA-Binding Proteins, pubmed-meshheading:21613800-Disease Progression, pubmed-meshheading:21613800-Female, pubmed-meshheading:21613800-Gastrointestinal Stromal Tumors, pubmed-meshheading:21613800-Genotype, pubmed-meshheading:21613800-Humans, pubmed-meshheading:21613800-Loss of Heterozygosity, pubmed-meshheading:21613800-Male, pubmed-meshheading:21613800-Microsatellite Repeats, pubmed-meshheading:21613800-Middle Aged, pubmed-meshheading:21613800-Mutation, pubmed-meshheading:21613800-Proto-Oncogene Proteins c-kit, pubmed-meshheading:21613800-RNA, Messenger, pubmed-meshheading:21613800-Receptor, Platelet-Derived Growth Factor alpha, pubmed-meshheading:21613800-Transcription Factors
pubmed:year
2011
pubmed:articleTitle
Heterozygosity loss at 22q and lack of INI1 gene mutation in gastrointestinal stromal tumor.
pubmed:affiliation
Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. hidetaka @ surgpath.med.kyushu-u.ac.jp
pubmed:publicationType
Journal Article