Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
24
pubmed:dateCreated
2011-6-15
pubmed:abstractText
2D and 3D cryo-electron microscopy, together with adsorption kinetics assays of Cb13 and CbK phage-infected Caulobacter crescentus, provides insight into the mechanisms of infection. Cb13 and CbK actively interact with the flagellum and subsequently attach to receptors on the cell pole. We present evidence that the first interaction of the phage with the bacterial flagellum takes place through a filament on the phage head. This contact with the flagellum facilitates concentration of phage particles around the receptor (i.e., the pilus portals) on the bacterial cell surface, thereby increasing the likelihood of infection. Phage head filaments have not been well characterized and their function is described here. Phage head filaments may systematically underlie the initial interactions of phages with their hosts in other systems and possibly represent a widespread mechanism of efficient phage propagation.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-10449785, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-10880436, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-11448025, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-12581350, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-14220656, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-14328417, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-16530048, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-16803630, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-16904341, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-17383677, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-18198338, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-18363791, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-18363799, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-18627889, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-18689468, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-18691905, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-19459952, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-20472802, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-2536661, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-2914863, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-334726, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-3792824, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-405372, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-407126, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4111056, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4132371, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4193836, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4210589, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4593496, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4635986, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4767460, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4820673, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4918241, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-4986906, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-5318403, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-5495512, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-5602462, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-5969754, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-6106721, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-6109706, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-6322001, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-7097844, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-841867, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-873885, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-873890, http://linkedlifedata.com/resource/pubmed/commentcorrection/21613567-8742726
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1091-6490
pubmed:author
pubmed:issnType
Electronic
pubmed:day
14
pubmed:volume
108
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9963-8
pubmed:dateRevised
2011-9-30
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Alternative mechanism for bacteriophage adsorption to the motile bacterium Caulobacter crescentus.
pubmed:affiliation
Division of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural