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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-7-3
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pubmed:abstractText |
Possible risk factors for abnormal Papanicolaou smear were investigated in a population-based cross-sectional study. From Nuuk (Greenland) and Nykøbing Falster (Denmark), random samples of 800 women aged 20-39 years were drawn. Totals of 586 and 661 women were included in Greenland and Denmark, respectively. All women went through a personal interview, and had a gynecologic examination including a PAP smear and cervical swab for HPV analysis. A blood sample was taken for analysis of HSV type specific antibodies. Multiple sexual partners was the most important risk factor for abnormal cervical cytology (OR = 4.2). An infectious etiology was also indirectly supported by a relatively protective effect of barrier contraceptive methods (OR = 0.6). The simultaneous finding of HPV 16/18 as a significant risk factor (OR = 2.4) cannot be taken uncritically as support for a causal effect of this HPV type, since such a relationship between cytological changes of the cervix and HPV infection could also emerge if the positive PAP smear was not just a measure of intra-epithelial neoplasia but also an expression of the infection itself on the cervix.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-6349
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
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pubmed:pagination |
79-86
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2161172-Adult,
pubmed-meshheading:2161172-Contraception Behavior,
pubmed-meshheading:2161172-Cross-Sectional Studies,
pubmed-meshheading:2161172-Denmark,
pubmed-meshheading:2161172-Female,
pubmed-meshheading:2161172-Greenland,
pubmed-meshheading:2161172-Herpes Genitalis,
pubmed-meshheading:2161172-Humans,
pubmed-meshheading:2161172-Papillomaviridae,
pubmed-meshheading:2161172-Risk Factors,
pubmed-meshheading:2161172-Sexual Behavior,
pubmed-meshheading:2161172-Smoking,
pubmed-meshheading:2161172-Tumor Virus Infections,
pubmed-meshheading:2161172-Uterine Cervical Dysplasia,
pubmed-meshheading:2161172-Uterine Cervical Neoplasms,
pubmed-meshheading:2161172-Vaginal Smears
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pubmed:year |
1990
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pubmed:articleTitle |
Abnormal Papanicolaou smear. A population-based study of risk factors in Greenlandic and Danish women.
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pubmed:affiliation |
Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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