21610145

Source:http://linkedlifedata.com/resource/pubmed/id/21610145

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0012899, umls-concept:C0013216, umls-concept:C0684249, umls-concept:C0871261, umls-concept:C1280500, umls-concept:C1414338, umls-concept:C1514162, umls-concept:C1516213, umls-concept:C1704632, umls-concept:C1706817, umls-concept:C1998811, umls-concept:C2911692
pubmed:issue	13
pubmed:dateCreated	2011-7-7
pubmed:abstractText	The purpose of this study is to test the hypothesis that eIF3a may regulate the expression of DNA repair proteins which, in turn, affects response of lung cancer patients to treatments by DNA-damaging anticancer drugs.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/DNA Repair Enzymes, http://linkedlifedata.com/resource/pubmed/chemical/EIF3A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Eukaryotic Initiation Factor-3, http://linkedlifedata.com/resource/pubmed/chemical/Platinum
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1078-0432
pubmed:author	pubmed-author:DongZi-ZhengZZ, pubmed-author:FengDe-YunDY, pubmed-author:HuangQiongQ, pubmed-author:LiuZhao-QianZQ, pubmed-author:ShenJieJ, pubmed-author:YinJi-YeJY, pubmed-author:ZhangJian-TingJT, pubmed-author:ZhongMei-ZuoMZ, pubmed-author:ZhouHong-HaoHH
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	17
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	4600-9
pubmed:meshHeading	pubmed-meshheading:21610145-Adult, pubmed-meshheading:21610145-Aged, pubmed-meshheading:21610145-Animals, pubmed-meshheading:21610145-Antineoplastic Agents, pubmed-meshheading:21610145-Cell Line, Transformed, pubmed-meshheading:21610145-Cell Line, Tumor, pubmed-meshheading:21610145-DNA Repair, pubmed-meshheading:21610145-DNA Repair Enzymes, pubmed-meshheading:21610145-Eukaryotic Initiation Factor-3, pubmed-meshheading:21610145-Female, pubmed-meshheading:21610145-Gene Expression, pubmed-meshheading:21610145-Gene Expression Regulation, Neoplastic, pubmed-meshheading:21610145-Gene Knockdown Techniques, pubmed-meshheading:21610145-Humans, pubmed-meshheading:21610145-Lung Neoplasms, pubmed-meshheading:21610145-Male, pubmed-meshheading:21610145-Mice, pubmed-meshheading:21610145-Middle Aged, pubmed-meshheading:21610145-NIH 3T3 Cells, pubmed-meshheading:21610145-Neoplasm Staging, pubmed-meshheading:21610145-Platinum, pubmed-meshheading:21610145-Treatment Outcome, pubmed-meshheading:21610145-Young Adult
pubmed:year	2011
pubmed:articleTitle	Effect of eIF3a on response of lung cancer patients to platinum-based chemotherapy by regulating DNA repair.
pubmed:affiliation	Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Xiang-Ya Hospital, Central South University, Changsha, Hunan, PR China.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't