Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-7-14
pubmed:abstractText
Several forms of epidermolysis bullosa (EB) present oral manifestations. Blistering of the (peri)oral mucosa affects the opening of the mouth, the mobility of the tongue and lips, thereby restricting oral functions. We describe the prevalence and characteristics of oral manifestations of EB in relation to loss of oral functions in a cross-sectional study of different types of EB patients using standardized measurement techniques. Twenty-two patients were included. The mobility of the mandible, lips and tongue was measured, the mandibular function impairment questionnaire (MFIQ) was filled out and additional questions regarding hindrance of EB during oral hygiene and intelligibility of speech (being understood) were asked in structured interviews. The median age was 11.8 yrs. Mobility of the mandible, tongue and lip was restricted, oral hygiene procedures were hindered in most patients. A data comparison was made between the recessive dystrophic EB (RDEB) and junctional EB (JEB) groups. Mandibular function was impaired in both groups but more severely in the RDEB-population. Intelligibility in both groups was almost unaffected. Restrictions in mobility of the mouth, tongue and lips are frequently present in EB patients. These are most severe in the RDEB group and support the clinical relevance of optimizing symptomatic treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1167-1122
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
405-9
pubmed:meshHeading
pubmed-meshheading:21609900-Adolescent, pubmed-meshheading:21609900-Adult, pubmed-meshheading:21609900-Biopsy, pubmed-meshheading:21609900-Blister, pubmed-meshheading:21609900-Child, pubmed-meshheading:21609900-Child, Preschool, pubmed-meshheading:21609900-Cross-Sectional Studies, pubmed-meshheading:21609900-Epidermolysis Bullosa Dystrophica, pubmed-meshheading:21609900-Female, pubmed-meshheading:21609900-Follow-Up Studies, pubmed-meshheading:21609900-Humans, pubmed-meshheading:21609900-Incidence, pubmed-meshheading:21609900-Infant, pubmed-meshheading:21609900-Male, pubmed-meshheading:21609900-Middle Aged, pubmed-meshheading:21609900-Mouth, pubmed-meshheading:21609900-Mouth Mucosa, pubmed-meshheading:21609900-Netherlands, pubmed-meshheading:21609900-Questionnaires, pubmed-meshheading:21609900-Severity of Illness Index, pubmed-meshheading:21609900-Skin, pubmed-meshheading:21609900-Speech, pubmed-meshheading:21609900-Young Adult
pubmed:articleTitle
Restrictions in oral functions caused by oral manifestations of epidermolysis bullosa.
pubmed:affiliation
Department of Oral and Maxillofacial Surgery, University Medical Centre, 9700 RB Groningen, The Netherlands. c.stellingsma@kchir.umcg.nl
pubmed:publicationType
Journal Article, Comparative Study