Source:http://linkedlifedata.com/resource/pubmed/id/21605683
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-7-11
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pubmed:abstractText |
A major advance in protein structure determination has been the advent of nanolitre-scale crystallization and (in a high-throughput environment) the development of robotic systems for storing and imaging crystallization trials. Most of these trials are carried out in 96-well (or higher density) plates and managing them is a significant information management challenge. We describe xtalPiMS, a web-based application for the management and monitoring of crystallization trials. xtalPiMS has a user-interface layer based on the standards of the Protein Information Management System (PiMS) and a database layer which links the crystallization trial images to the meta-data associated with a particular crystallization trial. The user interface has been optimized for the efficient monitoring of high-throughput environments with three different automated imagers and work to support a fourth imager is in progress, but it can even be of use without robotics. The database can either be a PiMS database or a legacy database for which a suitable mapping layer has been developed.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/,
http://linkedlifedata.com/resource/pubmed/grant/075491/Z/04,
http://linkedlifedata.com/resource/pubmed/grant/BBC5121101,
http://linkedlifedata.com/resource/pubmed/grant/BBC5121291,
http://linkedlifedata.com/resource/pubmed/grant/BBC5121371,
http://linkedlifedata.com/resource/pubmed/grant/BBC5121451
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1095-8657
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pubmed:author |
pubmed-author:ALEXHH,
pubmed-author:BerryIan MIM,
pubmed-author:BlakeRichardR,
pubmed-author:DanielEdE,
pubmed-author:DiproseJonathan MJM,
pubmed-author:EsnoufRobert MRM,
pubmed-author:GriffithsSusanne LSL,
pubmed-author:MorrisChrisC,
pubmed-author:OwensRaymond JRJ,
pubmed-author:StuartDavid IDI,
pubmed-author:WilsonKeith SKS
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
175
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
230-5
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pubmed:meshHeading |
pubmed-meshheading:21605683-Crystallography, X-Ray,
pubmed-meshheading:21605683-Database Management Systems,
pubmed-meshheading:21605683-Databases, Protein,
pubmed-meshheading:21605683-Information Management,
pubmed-meshheading:21605683-Online Systems,
pubmed-meshheading:21605683-Proteins,
pubmed-meshheading:21605683-User-Computer Interface
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pubmed:year |
2011
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pubmed:articleTitle |
xtalPiMS: a PiMS-based web application for the management and monitoring of crystallization trials.
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pubmed:affiliation |
CSED, STFC Daresbury Laboratory, Warrington WA44AD, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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