|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0012155,
umls-concept:C0019932,
umls-concept:C0028754,
umls-concept:C0037657,
umls-concept:C0040132,
umls-concept:C0043096,
umls-concept:C0086045,
umls-concept:C0175630,
umls-concept:C0205263,
umls-concept:C0299583,
umls-concept:C0439231,
umls-concept:C0442805,
umls-concept:C0497406,
umls-concept:C0547040,
umls-concept:C0681850,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C1880497,
umls-concept:C1996904,
umls-concept:C2349001,
umls-concept:C2697811
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2011-7-12
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|
pubmed:abstractText |
Short-term energy deprivation reduces leptin concentrations and alters the levels of circulating hormones of the hypothalamic-pituitary-peripheral axis in lean subjects. Whether the reduction in leptin concentration during long-term weight loss in obese individuals is linked to the same neuroendocrine changes seen in lean, leptin-sensitive subjects remains to be fully clarified.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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|
pubmed:issn |
1479-683X
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
165
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
249-54
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:21602313-Adult,
pubmed-meshheading:21602313-Aged,
pubmed-meshheading:21602313-Caloric Restriction,
pubmed-meshheading:21602313-Diet, Reducing,
pubmed-meshheading:21602313-Drug Administration Schedule,
pubmed-meshheading:21602313-Female,
pubmed-meshheading:21602313-Humans,
pubmed-meshheading:21602313-Leptin,
pubmed-meshheading:21602313-Male,
pubmed-meshheading:21602313-Middle Aged,
pubmed-meshheading:21602313-Obesity,
pubmed-meshheading:21602313-Osmolar Concentration,
pubmed-meshheading:21602313-Overweight,
pubmed-meshheading:21602313-Signal Transduction,
pubmed-meshheading:21602313-Somatomedins,
pubmed-meshheading:21602313-Thyroid Gland,
pubmed-meshheading:21602313-Thyroid Hormones,
pubmed-meshheading:21602313-Time Factors,
pubmed-meshheading:21602313-Weight Loss,
pubmed-meshheading:21602313-Young Adult
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pubmed:year |
2011
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|
pubmed:articleTitle |
Leptin administration to overweight and obese subjects for 6 months increases free leptin concentrations but does not alter circulating hormones of the thyroid and IGF axes during weight loss induced by a mild hypocaloric diet.
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pubmed:affiliation |
Division of Endocrinology, Diabetes and Metabolism, Harvard Medical School and Harvard School of Public Health, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215, USA.
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|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II,
Research Support, N.I.H., Extramural
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