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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1990-6-14
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pubmed:abstractText |
The bleeding from an induced gastric mucosal lesion was monitored after intravenous administration of unfractionated heparin and enoxaparin, a low molecular weight heparin. The gastric mucosa was exposed in a chamber, which was superfused with saline and emptied at 1-min intervals for quantitation of bleeding. Both heparins prolonged the bleeding time and increased the blood loss dose-dependently. Five to ten times higher doses of enoxaparin (in terms of anti-Xa units) were required to achieve similar prolongation of the bleeding times as with unfractionated heparin. The results indicate a more favourable antihaemostatic effect of enoxaparin than of unfractionated heparin.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0036-5521
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
379-82
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2159654-Animals,
pubmed-meshheading:2159654-Bleeding Time,
pubmed-meshheading:2159654-Dose-Response Relationship, Drug,
pubmed-meshheading:2159654-Gastrointestinal Hemorrhage,
pubmed-meshheading:2159654-Heparin,
pubmed-meshheading:2159654-Heparin, Low-Molecular-Weight,
pubmed-meshheading:2159654-Male,
pubmed-meshheading:2159654-Rats,
pubmed-meshheading:2159654-Rats, Inbred Strains
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pubmed:year |
1990
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pubmed:articleTitle |
Gastric mucosal bleeding after unfractionated and low molecular weight heparin in rats.
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pubmed:affiliation |
Medical Dept., Haukeland University Hospital, Bergen, Norway.
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pubmed:publicationType |
Journal Article
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