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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1990-6-14
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pubmed:abstractText |
It has been documented that the activity of a specific promoter can be occluded by the presence of another promoter element upstream. We present evidence for a phenomenon contradictory to that predicted by the promoter occlusion theory. Transcription from the hamster aprt (adenine phosphoribosyltransferase) promoter was augmented instead of repressed in transfected mouse L cells when an upstream Moloney murine sarcoma virus enhancer-promoter element was induced with butyrate. Without an adjacent Moloney murine sarcoma virus element, butyrate could not activate the aprt promoter.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-2440339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-2467742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-286319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-3018539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-3022130,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-3530495,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-3554238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-3736674,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-3943125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-3952002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-4041012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6091052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6092682,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6092925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6174854,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6190012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6251548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6254003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6316266,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6363938,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-6690710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2159551-7460013
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2907-11
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2159551-Adenine Phosphoribosyltransferase,
pubmed-meshheading:2159551-Animals,
pubmed-meshheading:2159551-Base Sequence,
pubmed-meshheading:2159551-Butyrates,
pubmed-meshheading:2159551-Butyric Acid,
pubmed-meshheading:2159551-Butyric Acids,
pubmed-meshheading:2159551-Cricetinae,
pubmed-meshheading:2159551-Enhancer Elements, Genetic,
pubmed-meshheading:2159551-Gene Expression Regulation, Viral,
pubmed-meshheading:2159551-L Cells (Cell Line),
pubmed-meshheading:2159551-Mice,
pubmed-meshheading:2159551-Molecular Sequence Data,
pubmed-meshheading:2159551-Moloney murine sarcoma virus,
pubmed-meshheading:2159551-Nucleotide Mapping,
pubmed-meshheading:2159551-Pentosyltransferases,
pubmed-meshheading:2159551-Plasmids,
pubmed-meshheading:2159551-Promoter Regions, Genetic,
pubmed-meshheading:2159551-Restriction Mapping,
pubmed-meshheading:2159551-Ribonucleases,
pubmed-meshheading:2159551-Sarcoma Viruses, Murine,
pubmed-meshheading:2159551-Transcriptional Activation,
pubmed-meshheading:2159551-Transfection
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pubmed:year |
1990
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pubmed:articleTitle |
Transcriptional activation of the adenine phosphoribosyltransferase promoter by an upstream butyrate-induced Moloney murine sarcoma virus enhancer-promoter element.
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pubmed:affiliation |
Department of Biology, Indiana University, Bloomington 47405.
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pubmed:publicationType |
Journal Article
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